Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2837990 | 0.81 | SLC6A3 (0.33) | — | |
| Hydrochloric Acid SCHEMBL2839164 | 0.81 | MAPK1 (0.34) | PKMHTR6 | |
| SCHEMBL2842497 | 0.76 | SLC6A2 (0.38) | PKM | |
| SCHEMBL2845450 | 0.72 | DRD1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL2841018 | 0.72 | PKM (0.31) | PKM | |
| Hydrochloric Acid SCHEMBL2844305 | 0.71 | PNMT (0.39) | — | |
| SCHEMBL2836825 | 0.71 | SLC6A2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL2845492 | 0.70 | PKM (0.34) | PKM | |
| SCHEMBL11727643 | 0.70 | HRH1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL11726932 | 0.68 | HRH1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217031-B2 | Heteroaryl derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100048537-A1 | HETEROARYL DERIVATIVES | NIPPON SHINYAKU CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2141168-A1 | HETEROARYL DERIVATIVES | Nippon Shinyaku Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048537-A1 | HETEROARYL DERIVATIVES | OPRD1, OPRM1, OPRK1 | PKM 935/4885HTR6 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.