Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 3/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577937 | 0.72 | METAP2 (0.39) | ADORA2ATRPA1FGFR1FGFR2METAP2 | |
| SCHEMBL20488997 | 0.70 | TRPA1 (0.39) | ADORA2ATRPA1FGFR1FGFR2METAP2 | |
| SCHEMBL4453497 | 0.69 | NOTUM (0.32) | — | |
| SCHEMBL28360899 | 0.68 | ADORA2A (0.38) | ADORA2A | |
| SCHEMBL28357412 | 0.68 | ADORA2A (0.32) | ADORA2A | |
| SCHEMBL9521923 | 0.68 | NOTUM (0.35) | — | |
| SCHEMBL28360967 | 0.66 | QPCT (0.33) | — | |
| SCHEMBL5797082 | 0.65 | MAOB (0.35) | — | |
| SCHEMBL28361049 | 0.65 | ADORA2A (0.33) | ADORA2A | |
| SCHEMBL4310693 | 0.64 | NOS1 (0.41) | TRPA1FGFR1FGFR2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |