Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835717 | 0.83 | TRPM8 (0.34) | ACLY | |
| SCHEMBL2836445 | 0.82 | ACLY (0.39) | ACLYCYP11B2NPY5RFFAR1CASP6 | |
| SCHEMBL4022147 | 0.81 | METAP1 (0.51) | GRM5FFAR1METAP1 | |
| SCHEMBL564294 | 0.79 | GABRA1 (0.39) | ACLYCYP11B2GRM5NPY5RCASP6 | |
| SCHEMBL4019514 | 0.72 | NPC1 (0.44) | ACLYCYP11B2GRM5NPY5RP2RX7 | |
| SCHEMBL4018444 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL23499270 | 0.68 | CASP6 (0.40) | ACLYCYP11B2NPY5RCASP6GABRA1 | |
| SCHEMBL4162294 | 0.68 | — | — | |
| SCHEMBL4162350 | 0.68 | — | — | |
| SCHEMBL4021311 | 0.67 | TRPM8 (0.47) | FFAR1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709637-B2 | 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20070088026-A1 | 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi | METAVANTE CORPORATION | 2007-04-19 | — | — | US | disclosed |
| US-7153860-B2 | 5-Phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | disclosed |
| US-20040116429-A1 | 5-Phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi | BASF SE (DE) | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088026-A1 | 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi | DPYD, CBR3, RNGTT | ACLY 2487/4885CYP11B2 1535/4885GRM5 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.