Edetic Acid

Edetic Acid

SCHEMBL2837360

CC(=O)OC1CC(C)(C)N(O)C(C)(C)C1.CC(=O)OC1CC(C)(C)N(O)C(C)(C)C1.O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
KMT2A Q03164 2/20 0.42
TDP1 Q9NUW8 2/20 0.40
EYA2 O00167 1/20 0.40
APP P05067 1/20 0.40
ACE P12821 1/20 0.40
BLM P54132 2/20 0.39
PMP22 Q01453 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
ALOX15 P16050 1/20 0.39
DRD1 P21728 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
CYP2C19 P33261 1/20 0.39
ADRA1A P35348 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL1232034 1.00 TSHR (0.42) TSHRKMT2ATDP1EYA2APP
Edetic Acid SCHEMBL1232024 1.00 TSHR (0.42) TSHRKMT2ATDP1EYA2APP
Edetic Acid SCHEMBL1232030 1.00 TSHR (0.42) TSHRKMT2ATDP1EYA2APP
Edetic Acid SCHEMBL14237204 0.90 ALDH1A1 (0.37) TSHRKMT2ATDP1EYA2APP
Acetic Acid SCHEMBL13732260 0.83 KMT2A (0.51) TSHRKMT2AKDM4ELMNACHRM2
SCHEMBL241284 0.83 KMT2A (0.50) TSHRKMT2AKDM4ELMNACHRM2
SCHEMBL21236221 0.82 GAA (0.42) TSHRKMT2AALOX15GAAHTT
Edetic Acid SCHEMBL1231022 0.80 TDP1 (0.47) TSHRTDP1EYA2APPACE
Edetic Acid SCHEMBL1233013 0.80 TDP1 (0.47) TSHRTDP1EYA2APPACE
Edetic Acid SCHEMBL987564 0.80 TDP1 (0.47) TSHRTDP1EYA2APPACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2464739-B1 METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES BASF SE (DE) 2016-01-13 EP claimed
EP-1680541-B1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS BASF SE (DE) 2012-12-19 EP claimed
US-20120164162-A1 METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES BASF SE (DE) 2012-06-28 US claimed
EP-1499286-B1 STABILIZED BODY CARE PRODUCTS AND HOUSEHOLD PRODUCTS BASF SE (DE) 2010-04-07 EP claimed
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORP. 2007-04-12 US claimed
EP-1680541-A2 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS Ciba SC Holding AG (CH) 2006-07-19 EP claimed
US-20050220727-A1 Stabilized body care products, household products, textiles and fabrics CIBA CORPORATION 2005-10-06 US claimed
WO-2005042828-A2 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-05-12 WO claimed
EP-1499286-A1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS Ciba SC Holding AG (CH) 2005-01-26 EP claimed
WO-2003103622-A1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-12-18 WO claimed
US-6500303-B1 DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL; PROTECTION FROM ULTRAVIOLET, FLUORESCENT AND SUN LIGHT EXPOSURE CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-31 US claimed
US-20020124980-A1 Inhibition of pulp and paper yellowing using nitroxides, hydroxylamines and other coadditives SELTZER RAYMOND R (US) 2002-09-12 US claimed
US-6254724-B1 STABILIZING AMOUNT OF A HINDERED AMINE COMPOUND SELECTED DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL OR WHICH ARE THEIR HYDROXYLAMINE SALTS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-03 US claimed
US-10098849-B2 Anti-radical agents BASF SE (DE) 2018-10-16 US disclosed
US-9358195-B2 Stabilized body care products, household products, textiles and fabrics BASF SE (DE) 2016-06-07 US disclosed
EP-2464739-B1 METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES BASF SE (DE) 2016-01-13 EP disclosed
US-6447644-B1 PULP OR PAPER THAT STILL CONTAINS LIGNIN, AND A STERICALLY HINDERED AMINE, FOR EXAMPLE DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL CIBA SPECIALTY CHEMICALS CORPORATION 2002-09-10 US disclosed
US-6254724-B1 STABILIZING AMOUNT OF A HINDERED AMINE COMPOUND SELECTED DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL OR WHICH ARE THEIR HYDROXYLAMINE SALTS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-03 US disclosed
EP-1000032-A1 INHIBITION OF PULP AND PAPER YELLOWING USING NITROXIDES AND OTHER COADDITIVES Ciba SC Holding AG (CH) 2000-05-17 EP disclosed
WO-1999005108-A1 INHIBITION OF PULP AND PAPER YELLOWING USING NITROXIDES AND OTHER COADDITIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CUTA, NISCH, DSC1 TSHR 1658/4885KMT2A 1072/4885TDP1 628/4885
US-20050220727-A1 Stabilized body care products, household products, textiles and fabrics CUTA, DHRS9, DSC1 TSHR 1597/4885KMT2A 789/4885TDP1 530/4885
US-10098849-B2 Anti-radical agents NOS3, GSTO1, TXN2 TSHR 3772/4885KMT2A 3587/4885TDP1 1455/4885
US-20120164162-A1 METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES BBOX1, NEFM, NQO1 TSHR 4798/4885KMT2A 958/4885TDP1 2430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.