Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP known ✓ | O00591 | 2/20 | 0.42 |
| ▸ | GABRD known ✓ | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 known ✓ | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 known ✓ | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 known ✓ | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 known ✓ | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 known ✓ | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 known ✓ | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 known ✓ | P48169 | 2/20 | 0.42 |
| ▸ | GABRE known ✓ | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 known ✓ | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 known ✓ | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 known ✓ | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ known ✓ | Q9UN88 | 2/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39653 | 0.95 | TET2 (0.48) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL28358244 | 0.92 | TET2 (0.46) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL27842901 | 0.82 | FOLH1 (0.50) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL22802640 | 0.81 | OR51E2 (0.61) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL5081381 | 0.80 | ALDH1A1 (0.50) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL27622393 | 0.80 | ALDH1A1 (0.50) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL241573 | 0.80 | TET2 (0.55) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL5807652 | 0.80 | GABRP (0.40) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL754548 | 0.79 | GSTK1 (0.58) | FOLH1CYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL11615768 | 0.77 | TET2 (0.52) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110951031-B | High-hydrolysis-resistance polyurethane damping material and preparation method thereof | 安徽匠星联创新材料科技有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-110951031-A | High-hydrolysis-resistance polyurethane damping material and preparation method thereof | 安徽匠星联创新材料科技有限公司 | 2020-04-03 | — | — | CN | claimed |
| CN-110951031-B | High-hydrolysis-resistance polyurethane damping material and preparation method thereof | 安徽匠星联创新材料科技有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-110951031-B | High-hydrolysis-resistance polyurethane damping material and preparation method thereof | 安徽匠星联创新材料科技有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-110951031-A | High-hydrolysis-resistance polyurethane damping material and preparation method thereof | 安徽匠星联创新材料科技有限公司 | 2020-04-03 | — | — | CN | disclosed |
| CN-110951031-A | High-hydrolysis-resistance polyurethane damping material and preparation method thereof | 安徽匠星联创新材料科技有限公司 | 2020-04-03 | — | — | CN | disclosed |