SCHEMBL28375993

SCHEMBL28375993

Nc1ccc(NCOS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.51
KMT2A Q03164 4/20 0.44
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
CA12 O43570 2/20 0.41
PRMT1 Q99873 3/20 0.40
ALDH1A1 P00352 3/20 0.40
HTT P42858 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX12 P18054 1/20 0.40
CYP2C19 P33261 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 3/20 0.39
HTR6 P50406 2/20 0.39
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8768517 0.77 CA12 (0.51) KMT2ACA1CA2CA9CA12
SCHEMBL28440292 0.72 KEAP1 (0.53) KEAP1KMT2ACA1CA2CA9
SCHEMBL4823307 0.71 ALDH1A1 (0.65) KEAP1KMT2ACA1CA2CA9
SCHEMBL27371581 0.69 PARL (0.47) KMT2ACA1CA2CA9CA12
SCHEMBL347302 0.69 PSIP1 (0.54) KMT2ACA1CA2CA9CA12
SCHEMBL28291801 0.69 TSHR (0.52) KMT2ACA1CA2CA9CA12
SCHEMBL6115076 0.68 PARL (0.50) KMT2ACA1CA2CA9CA12
SCHEMBL3449015 0.68 PARL (0.50) KMT2ACA1CA2CA9CA12
SCHEMBL27779751 0.68 CA2 (0.46) KEAP1CA1CA2CA9CA12
SCHEMBL1459166 0.68 TDP1 (0.67) KEAP1CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110878175-B Acid dye for dyeing nylon fiber and preparation method thereof 金华双宏化工有限公司 2021-05-25 CN disclosed
CN-110878175-A Acid dye for dyeing nylon fiber and preparation method thereof 金华双宏化工有限公司 2020-03-13 CN disclosed