Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30192181 | 1.00 | IDO1 (0.57) | IDO1GPR35MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7570994 | 0.98 | IDO1 (0.55) | IDO1GPR35MAPTMEN1KMT2A | |
| SCHEMBL1463479 | 0.79 | IDO1 (0.57) | IDO1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL3277817 | 0.79 | IDO1 (0.35) | IDO1GPR35TGM2CES1 | |
| SCHEMBL4021639 | 0.77 | IDO1 (0.33) | IDO1GPR35MAPTKMT2AHTT | |
| SCHEMBL3273478 | 0.76 | DGAT1 (0.45) | IDO1GPR35KMT2AKDM4EGLA | |
| SCHEMBL10254523 | 0.76 | GPR35 (0.35) | IDO1GPR35TSHRRAB9AKDM4E | |
| SCHEMBL1629842 | 0.76 | ALOX5AP (0.36) | IDO1GPR35MAPTMEN1KMT2A | |
| SCHEMBL13404775 | 0.76 | JAK2 (0.41) | MAPTMEN1KMT2AHTTJAK2 | |
| SCHEMBL27363041 | 0.76 | ALDH1A1 (0.42) | MAPTMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182303-B1 | THERMODYNAMICALLY STABLE FORM OF SCO-101 | SCANDION ONCOLOGY AS (DK) | 2023-11-29 | — | — | EP | claimed |
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-08 | — | — | US | claimed |
| EP-2155700-B1 | BETA-KETO-AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH AS (DK) | 2010-10-06 | — | — | EP | disclosed |
| US-20100144736-A1 | NOVEL BIPHENYL THIO-UREA DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-06-10 | — | — | US | disclosed |
| US-20100144736-A1 | NOVEL BIPHENYL THIO-UREA DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-06-10 | — | — | US | disclosed |
| US-20100144736-A1 | NOVEL BIPHENYL THIO-UREA DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-06-10 | — | — | US | disclosed |
| US-20100137381-A1 | ACETAMIDE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-06-03 | — | — | US | disclosed |
| US-20100137387-A1 | BETA-KETO-AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-06-03 | — | — | US | disclosed |
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-08 | — | — | US | disclosed |
| EP-2155700-A1 | BETA-KETO-AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-02-24 | — | — | EP | disclosed |
| EP-2152677-A1 | ACETAMIDE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-02-17 | — | — | EP | disclosed |
| WO-2004022529-A2 | DIARYLUREA DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 2004-03-18 | — | — | WO | disclosed |
| US-6696475-B2 | N-PHENYL-N'-(2-CARBOXYPHENYL) UREA, FOR EXAMPLE; CHLORIDE CHANNEL BLOCKERS; SUCH AS FOR TREATING BONE METABOLIC DISORDERS | NEUROSEARCH A/S (DK) | 2004-02-24 | — | — | US | disclosed |
| EP-0977741-B1 | SUBSTITUTED PHENYL DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH AS (DK) | 2003-09-03 | — | — | EP | disclosed |
| CN-1118462-C | Substituted phenyl derivatives, their preparation and use | NEUROSEARCH AS (DK) | 2003-08-20 | — | — | CN | disclosed |
| US-20020037905-A1 | Substituted phenyl derivatives, their preparation and use | ANIONA APS (DK) | 2002-03-28 | — | — | US | disclosed |
| US-6297261-B1 | POTENT CHLORIDE CHANNEL BLOCKERS; TREATMENT OF SICKLE CELL ANEMIA, BRAIN EDEMA FOLLOWING ISCHAEMIA OR TUMORS, DIARRHEA, HYPERTENSION (DIURETIC), OSTEOPOROSIS, AND FOR THE REDUCTION OF THE INTRAOCULAR PRESSURE | NEUROSEARCH A/S (DK) | 2001-10-02 | — | — | US | disclosed |
| CN-1253553-A | Substituted phenyl derivatives, their preparation and use | NEUROSEARCH AS (DK) | 2000-05-17 | — | — | CN | disclosed |
| EP-0977741-A1 | SUBSTITUTED PHENYL DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998047879-A1 | SUBSTITUTED PHENYL DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 1998-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137387-A1 | BETA-KETO-AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | KCNAB1, KCNJ2, KCNN3 | IDO1 4173/4885GPR35 1406/4885MAPT 2006/4885 |
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | TRPV1, TRPA1, TRPM8 | IDO1 4497/4885GPR35 1129/4885MAPT 1755/4885 |
| US-20020037905-A1 | Substituted phenyl derivatives, their preparation and use | KCNB1, KCNH2, KCNJ2 | IDO1 2512/4885GPR35 952/4885MAPT 3787/4885 |
| US-20100137381-A1 | ACETAMIDE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | KCNJ2, KCNJ1, KCNN2 | IDO1 4391/4885GPR35 1562/4885MAPT 1884/4885 |
| US-20100144736-A1 | NOVEL BIPHENYL THIO-UREA DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNJ1, KCNJ2, KCNB1 | IDO1 2360/4885GPR35 991/4885MAPT 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.