Water

Water

SCHEMBL2838856

O.O.O.[Hf]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL18941383 1.00
Water SCHEMBL489954 1.00
Water SCHEMBL28992320 1.00
Water SCHEMBL1331926 1.00
Water SCHEMBL20582743 1.00
Water SCHEMBL549634 1.00
Water SCHEMBL28664843 1.00
Water SCHEMBL23327033 0.82
Water SCHEMBL21066928 0.82
Water SCHEMBL20573312 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118249774-B Bulk acoustic wave resonator and preparation method thereof 河源市艾佛光通科技有限公司 2024-09-20 CN claimed
CN-118249774-A Bulk acoustic wave resonator and preparation method thereof 河源市艾佛光通科技有限公司 2024-06-25 CN claimed
US-8460628-B2 Spiro compounds BASF SE (DE) 2013-06-11 US claimed
EP-2222687-B1 SPIRO COMPOUNDS BASF SE (DE) 2012-09-26 EP claimed
US-20100294673-A1 POROUS MONOLITHIC MATERIALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-11-25 US claimed
US-20100284882-A1 SPIRO COMPOUNDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-11-11 US claimed
US-7750354-B2 Solid-state imaging device and manufacturing method for the same PANASONIC CORPORATION (JP) 2010-07-06 US claimed
US-20080303108-A1 SOLID-STATE IMAGING DEVICE AND MANUFACTURING METHOD FOR THE SAME MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-12-11 US claimed
US-20060169878-A1 Solid-state imaging device and manufacturing method for the same PANASONIC CORPORATION (JP) 2006-08-03 US claimed
CN-118249774-B Bulk acoustic wave resonator and preparation method thereof 河源市艾佛光通科技有限公司 2024-09-20 CN disclosed
CN-118249774-A Bulk acoustic wave resonator and preparation method thereof 河源市艾佛光通科技有限公司 2024-06-25 CN disclosed
US-11222997-B2 Luminous body, light emitting film, light emitting diode and light emitting device having luminous body LG DISPLAY CO., LTD. (KR) 2022-01-11 US disclosed
EP-3474329-A1 LUMINOUS BODY, LIGHT EMITTING FILM, LIGHT EMITTING DIODE AND LIGHT EMITTING DEVICE HAVING LUMINOUS BODY LG Display Co., Ltd. (KR) 2019-04-24 EP disclosed
US-20190115507-A1 LUMINOUS BODY, LIGHT EMITTING FILM, LIGHT EMITTING DIODE AND LIGHT EMITTING DEVICE HAVING LUMINOUS BODY LG DISPLAY CO., LTD. (KR) 2019-04-18 US disclosed
US-7750354-B2 Solid-state imaging device and manufacturing method for the same PANASONIC CORPORATION (JP) 2010-07-06 US disclosed
US-20090225204-A1 SOLID STATE IMAGING DEVICE AND CAMERA PANASONIC CORPORATION (JP) 2009-09-10 US disclosed
US-20080303108-A1 SOLID-STATE IMAGING DEVICE AND MANUFACTURING METHOD FOR THE SAME MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-12-11 US disclosed
US-7416915-B2 Solid-state imaging device and manufacturing method for the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-08-26 US disclosed
US-20070188635-A1 Solid-state imaging device and camera PANASONIC CORPORATION (JP) 2007-08-16 US disclosed
US-20060169878-A1 Solid-state imaging device and manufacturing method for the same PANASONIC CORPORATION (JP) 2006-08-03 US disclosed