Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626234 | 0.83 | KCNH2 (0.46) | KDM4CKCNH2AKT1AKT2LMNA | |
| SCHEMBL8540552 | 0.78 | LMNA (0.47) | LTA4HMMP1LMNAMAPK1SCN9A | |
| SCHEMBL19630376 | 0.77 | ALDH1A1 (0.58) | MAPK1TDP1NPC1RAB9A | |
| SCHEMBL4733455 | 0.72 | CYP19A1 (0.53) | KCNH2LMNAMAPK1SCN9APDE4B | |
| SCHEMBL22061918 | 0.71 | LMNA (0.44) | LTA4HMMP1LMNAMAPK1SCN9A | |
| SCHEMBL30838799 | 0.70 | LTA4H (0.39) | LTA4HMMP1LMNASCN9A | |
| SCHEMBL1680381 | 0.69 | LTA4H (0.67) | LTA4HLMNATDP1NPC1SCN4A | |
| SCHEMBL3373407 | 0.68 | AKT2 (0.64) | AKT1AKT2LMNACHEK1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL3454484 | 0.67 | LTA4H (0.63) | LTA4HLMNATDP1NPC1SCN4A | |
| SCHEMBL30047550 | 0.67 | LTA4H (0.63) | LTA4HLMNANPC1SCN4ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116565-B | 2-aryl-4- (4-pyrazolyloxy) pyridine compound, preparation method thereof, pharmaceutical composition and application thereof | 中科利健制药(广州)有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111116565-A | 2-aryl-4- (4-pyrazolyloxy) pyridine compound, preparation method thereof, pharmaceutical composition and application thereof | 中科利健制药(广州)有限公司 | 2020-05-08 | — | — | CN | disclosed |