SCHEMBL30838799

SCHEMBL30838799

c1cc(Oc2cc[nH]c2)ccn1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.39
MMP1 P03956 4/20 0.33
SCN9A Q15858 1/20 0.33
BRAF P15056 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MMP13 P45452 1/20 0.30
MAP4K4 O95819 1/20 0.30
TNK2 Q07912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17394554 0.83 TSHR (0.33) LTA4H
SCHEMBL8540552 0.78 LMNA (0.47) LTA4HMMP1SCN9ALMNAMAPT
SCHEMBL7759460 0.77 LTA4H (0.57) LTA4H
SCHEMBL28129946 0.76 LTA4H (0.55) LTA4H
SCHEMBL3256252 0.74 ALDH1A1 (0.61) LTA4HMAPT
SCHEMBL22061918 0.71 LMNA (0.44) LTA4HMMP1SCN9ALMNAMAPT
SCHEMBL28396334 0.70 KDM4C (0.46) LTA4HMMP1SCN9ALMNA
SCHEMBL1680381 0.69 LTA4H (0.67) LTA4HLMNAMAPTMMP13
SCHEMBL3256253 0.67 PARP10 (0.68) MAPT
Ammonia Solution, Strong SCHEMBL3454484 0.67 LTA4H (0.63) LTA4HLMNAMAPTMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12117439-B2 Compositions and methods for using fixed biological samples 10X GENOMICS, INC. (US) 2024-10-15 US disclosed
US-20240125772-A1 COMPOSITIONS AND METHODS FOR USING FIXED BIOLOGICAL SAMPLES IN PARTITION-BASED ASSAYS 10X GENOMICS, INC. 2024-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12117439-B2 Compositions and methods for using fixed biological samples FBL, ALKBH1, NOP2 LTA4H 1783/4885MMP1 1084/4885SCN9A 4279/4885
US-20240125772-A1 COMPOSITIONS AND METHODS FOR USING FIXED BIOLOGICAL SAMPLES IN PARTITION-BASED ASSAYS FBL, DIS3, ALKBH1 LTA4H 1861/4885MMP1 1461/4885SCN9A 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.