Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083293 | 0.85 | XDH (0.42) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28248341 | 0.84 | MAPT (0.49) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL28226587 | 0.83 | LMNA (0.41) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28395393 | 0.83 | MAPT (0.57) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28226658 | 0.83 | PTGS2 (0.54) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28284102 | 0.83 | LMNA (0.41) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL244194 | 0.83 | MAPK1 (0.56) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL7402133 | 0.81 | SMN1; SMN2 (0.42) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28400665 | 0.81 | LMNA (0.65) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28227470 | 0.81 | LOXL2 (0.42) | MEN1KMT2ANPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203450-B | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |