Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416960 | 0.84 | RAB9A (0.41) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL28409571 | 0.82 | MAPT (0.40) | ALDH1A1MAPTADRB1RAB9AMGLL | |
| SCHEMBL28408861 | 0.82 | TRPA1 (0.40) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL28409512 | 0.82 | CASP6 (0.40) | ALDH1A1MAPTGAAMEN1CASP6 | |
| SCHEMBL28409989 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPTGAAMGLLSLC6A2 | |
| SCHEMBL28822189 | 0.82 | TRPA1 (0.37) | ALDH1A1MEN1KMT2AL3MBTL1MGLL | |
| SCHEMBL28407412 | 0.78 | DRD2 (0.42) | ALDH1A1MAPTHTTKCNH2ALOX5 | |
| SCHEMBL28412512 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAKMT2AL3MBTL1 | |
| SCHEMBL28410012 | 0.76 | ABL1 (0.41) | ALDH1A1MAPTL3MBTL1ADRB1RAB9A | |
| SCHEMBL28403820 | 0.75 | HSD17B3 (0.37) | CASP6HSP90AA1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116487-B | Phthalazine compound, and synthetic method and application thereof | 西北农林科技大学 | 2022-08-23 | — | — | CN | claimed |
| CN-111116487-B | Phthalazine compound, and synthetic method and application thereof | 西北农林科技大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-111116487-A | Phthalazine compound, and synthetic method and application thereof | 西北农林科技大学 | 2020-05-08 | — | — | CN | disclosed |