Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408807 | 0.85 | RAB9A (0.44) | MAPTNPC1LMNAALDH1A1RAB9A | |
| SCHEMBL28404573 | 0.82 | ALDH1A1 (0.40) | MAPTNPC1ADRB1MGLLALDH1A1 | |
| SCHEMBL28408861 | 0.80 | TRPA1 (0.40) | MAPTNPC1LMNAALDH1A1RAB9A | |
| SCHEMBL28822189 | 0.79 | TRPA1 (0.37) | MGLLALDH1A1 | |
| SCHEMBL28409989 | 0.79 | ALDH1A1 (0.39) | MAPTNOTUMMGLLALDH1A1FAAH | |
| SCHEMBL28409512 | 0.79 | CASP6 (0.40) | MAPTADRB1FGFR1NOTUMMGLL | |
| SCHEMBL28407412 | 0.76 | DRD2 (0.42) | MAPTNOTUMALDH1A1DRD2KCNH2 | |
| SCHEMBL28412512 | 0.76 | ALDH1A1 (0.56) | MAPTNOTUMLMNAALDH1A1NPSR1 | |
| SCHEMBL28416960 | 0.75 | RAB9A (0.41) | MAPTNPC1LMNAALDH1A1RAB9A | |
| SCHEMBL28403820 | 0.73 | HSD17B3 (0.37) | NPSR1DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116487-B | Phthalazine compound, and synthetic method and application thereof | 西北农林科技大学 | 2022-08-23 | — | — | CN | claimed |
| CN-111116487-B | Phthalazine compound, and synthetic method and application thereof | 西北农林科技大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-111116487-A | Phthalazine compound, and synthetic method and application thereof | 西北农林科技大学 | 2020-05-08 | — | — | CN | disclosed |