Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414511 | 0.78 | PDK1 (0.38) | HRH3PDK1NPSR1 | |
| SCHEMBL22732611 | 0.76 | HRH3 (0.42) | HRH3HTR4ALDH1A1PKMEPHA2 | |
| SCHEMBL22732727 | 0.76 | HRH3 (0.42) | HRH3HTR4ALDH1A1PKMEPHA2 | |
| SCHEMBL29233712 | 0.75 | PDK1 (0.47) | HRH3PDK1NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30133730 | 0.74 | HRH3 (0.41) | HRH3HTR4ALDH1A1PKMEPHA2 | |
| SCHEMBL23710030 | 0.72 | HRH3 (0.47) | HRH3HTR4ALDH1A1PKMEPHA2 | |
| SCHEMBL28515787 | 0.69 | PDK1 (0.39) | PDK1 | |
| SCHEMBL22732893 | 0.69 | HTR4 (0.43) | HRH3HTR4ALDH1A1PKMEPHA2 | |
| SCHEMBL8845308 | 0.69 | LMNA (0.64) | NPSR1ALDH1A1 | |
| SCHEMBL23049101 | 0.69 | LMNA (0.64) | NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938068-B | N- (morpholin-2-ylmethyl) amide derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-110938068-A | N- (morpholin-2-ylmethyl) amide derivatives and their use | 广东东阳光药业有限公司 | 2020-03-31 | — | — | CN | disclosed |