Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.34 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28433432 | 0.69 | MAPT (0.38) | MEN1MAPTKMT2AHPGDALDH1A1 | |
| SCHEMBL13665689 | 0.67 | HSD11B1 (0.41) | MEN1MAPTKMT2AHPGDALDH1A1 | |
| SCHEMBL30393019 | 0.61 | HRH3 (0.45) | ALDH1A1GAARAB9ACYP3A4CYP2D6 | |
| SCHEMBL29089042 | 0.60 | KDM4E (0.32) | ALDH1A1GAACA1CA2EGFR | |
| SCHEMBL5805189 | 0.59 | MAPT (0.64) | MEN1MAPTKMT2AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11037664 | 0.59 | TSHR (0.34) | ALDH1A1PDE5APRKCZTSHR | |
| SCHEMBL23602995 | 0.57 | AKR1C3 (0.38) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL19707383 | 0.57 | CYP2C9 (0.44) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| SCHEMBL13296173 | 0.55 | FAAH (0.54) | MEN1MAPTKMT2AHPGDALDH1A1 | |
| SCHEMBL5713339 | 0.55 | LOX (0.63) | LOXLOXL3LOXL4LOXL2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270361-A1 | Substituted pyrazole derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270361-A1 | Substituted pyrazole derivatives and use thereof | CBR3, CBR1, NOX5 | LOX 1323/4885LOXL3 2019/4885LOXL4 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.