SCHEMBL2843422

SCHEMBL2843422

CCC(=O)OCC(C)(C)C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.38
ALDH1A1 P00352 3/20 0.34
CYP1A2 P05177 2/20 0.34
BLM P54132 2/20 0.34
HIF1A Q16665 2/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
WRN Q14191 1/20 0.34
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2846232 0.83 ALDH1A1 (0.43) ALDH1A1CYP1A2BLMHIF1AMEN1
SCHEMBL2847460 0.80 DGKA (0.46) ALDH1A1CYP1A2MEN1CYP3A4MAPT
SCHEMBL10572750 0.79 DGKA (0.44) ALDH1A1CYP1A2MEN1CYP3A4MAPT
SCHEMBL9630407 0.79 MEN1 (0.30) ALDH1A1CYP1A2BLMHIF1AMEN1
SCHEMBL4425044 0.79 DGKA (0.44) ALDH1A1CYP1A2MEN1CYP3A4MAPT
SCHEMBL23521357 0.79 DGKA (0.44) ALDH1A1CYP1A2MEN1CYP3A4MAPT
SCHEMBL2845569 0.79 DGKA (0.53) ALDH1A1MEN1CYP3A4MAPTTSHR
SCHEMBL3095915 0.78 MMP1 (0.40) ALDH1A1TSHR
SCHEMBL9935881 0.77 DGKA (0.56) ALDH1A1MEN1MAPTTSHRKMT2A
SCHEMBL340251 0.77 DGKA (0.56) ALDH1A1MEN1MAPTTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651875-B1 AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-30 EP claimed
CN-103261145-B There is the amine of secondary aliphatic amino group SIKA TECHNOLOGY AG (CH) 2016-04-13 CN claimed
US-9290603-B2 Amines having secondary aliphatic amino groups SIKA TECHNOLOGY AG (CH) 2016-03-22 US claimed
EP-2651875-A1 AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS Sika Technology AG (CH) 2013-10-23 EP claimed
US-20130237681-A1 AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2013-09-12 US claimed
CN-103261145-A Amines having secondary aliphatic amino groups SIKA TECHNOLOGY AG 2013-08-21 CN claimed
WO-2012080264-A1 AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2012-06-21 WO claimed
EP-2465842-A1 Amines with secondary aliphatic amines Sika Technology AG (CH) 2012-06-20 EP claimed
US-20100130674-A1 METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT SIKA TECHNOLOGY AG (CH) 2010-05-27 US claimed
CN-101646704-A Method for the production of polyurethane compositions with a low isocyanate monomer content SIKA TECHNOLOGY AG CH 2010-02-10 CN claimed
EP-2132246-A1 METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT Sika Technology AG (CH) 2009-12-16 EP claimed
WO-2008116927-A1 METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT SIKA TECHNOLOGY AG (CH) 2008-10-02 WO claimed
EP-1975187-A1 Method for manufacturing polyurethane compounds with low isocyanate-monomer content Sika Technology AG (CH) 2008-10-01 EP claimed
EP-4077299-B1 SUBSTITUTED 4-METHYLENE-TETRAHYDROPYRANS, 4-METHYL-DIHYDROPYRANS AND 4-METHYL-TETRAHYDROPYRANS AND USE THEREOF AS AROMA CHEMICALS BASF SE (DE) 2026-04-01 EP disclosed
US-12421203-B2 Substituted 4-methylene-tetrahydropyrans, 4-methyl-dihydropyrans and 4-methyl-tetrahydropyrans and use thereof as aroma chemicals BASF SE (DE) 2025-09-23 US disclosed
CN-114846002-B Substituted 4-methylene-tetrahydropyrans, 4-methyl-dihydropyrans and 4-methyl-tetrahydropyrans and their use as fragrance chemicals 巴斯夫欧洲公司 2024-09-27 CN disclosed
CN-1329421-C Two-component polyurethane compositions having high early strength SIKA TECHNOLOGY AG (CH) 2007-08-01 CN disclosed
US-20070004893-A1 TWO-CONSTITUENT POLYURETHANE COMPOSITION HAVING HIGH EARLY STRENGTH SIKA TECHNOLOGY AG (CH) 2007-01-04 US disclosed
US-20060052522-A1 Two-constituent polyurethance composition having high early strength SIKA TECHNOLOGY AG (CH) 2006-03-09 US disclosed
CN-1610709-A Two-constituent polyurethane composition having high early strength SIKA TECHNOLOGY AG (CH) 2005-04-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130237681-A1 AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS AAAS, PNMT, PARG NAAA 114/4885ALDH1A1 1074/4885CYP1A2 3174/4885
US-12421203-B2 Substituted 4-methylene-tetrahydropyrans, 4-methyl-dihydropyrans and 4-methyl-tetrahydropyrans and use thereof as aroma chemicals DHPS, HPD, DPYD NAAA 1592/4885ALDH1A1 49/4885CYP1A2 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.