Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937656 | 0.90 | MEN1 (0.49) | KDM4EALDH1A1KMT2AMEN1MCL1 | |
| SCHEMBL2845133 | 0.84 | MEN1 (0.50) | KDM4EALDH1A1KMT2AMEN1SYK | |
| SCHEMBL187309 | 0.81 | MEN1 (0.50) | ALDH1A1KMT2AMEN1CCR2MAPT | |
| Hydrochloric Acid SCHEMBL10734951 | 0.80 | MEN1 (0.53) | KMT2AMEN1CCR2SOS1USP2 | |
| SCHEMBL10933064 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1SYKCCR2 | |
| SCHEMBL10939339 | 0.79 | MEN1 (0.50) | KDM4EALDH1A1KMT2AMEN1CCR2 | |
| SCHEMBL1821251 | 0.78 | HTR7 (0.51) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL2930491 | 0.78 | CCR2 (0.51) | KDM4EALDH1A1KMT2AMEN1CCR2 | |
| SCHEMBL8742178 | 0.78 | MEN1 (0.48) | KMT2AMEN1SYKCCR2SOS1 | |
| Hydrochloric Acid SCHEMBL9486649 | 0.78 | HTR7 (0.50) | KDM4EKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100021541-A1 | Microparticulate form of a Tetrahydropyridine derivative | SANOFI-AVENTIS (FR) | 2010-01-28 | — | — | US | disclosed |
| US-20080255365-A1 | Microparticulate form of a Tetrahydropyridine derivative | SANOFI-AVENTIS (FR) | 2008-10-16 | — | — | US | disclosed |
| US-20020192292-A1 | Microparticulate form of a tetrahydropyridin derivative | SANOFI-AVENTIS (FR) | 2002-12-19 | — | — | US | disclosed |
| US-20020028247-A1 | MICRO-PARTICULATE FORM OF A TETRAHYDROPYRIDIN DERIVATIVE | SANOFI-SYNTHEALBO (FR) | 2002-03-07 | — | — | US | disclosed |
| EP-0101381-B1 | ANOREXIC TRIFLUOROMETHYL PHENYL TETRAHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI S.A. (FR) | 1985-12-04 | — | — | EP | disclosed |
| US-4521428-A | Anorexigenic trifluoromethylphenyltetrahydropyridines and pharmaceutical compositions containing them | SANOFI (FR) | 1985-06-04 | — | — | US | disclosed |
| EP-0101381-A1 | Anorexic trifluoromethyl phenyl tetrahydropyridines, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1984-02-22 | — | — | EP | disclosed |