Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 3/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553024 | 0.85 | PKM (0.75) | LMNAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL7335926 | 0.80 | NR3C1 (0.64) | LMNAALDH1A1NPSR1HTTPKM | |
| SCHEMBL7335037 | 0.80 | NR3C1 (0.58) | LMNAALDH1A1NPSR1HPGDHTT | |
| SCHEMBL8549210 | 0.77 | NR3C1 (0.64) | LMNAALDH1A1NPSR1HTTPKM | |
| SCHEMBL7326548 | 0.77 | NR3C1 (0.60) | LMNAALDH1A1NPSR1PKMCNR2 | |
| SCHEMBL6295935 | 0.77 | ESR1 (0.67) | LMNAALDH1A1NPSR1HTTCNR2 | |
| SCHEMBL5461742 | 0.76 | LMNA (0.65) | LMNAALDH1A1NPSR1HPGDHTT | |
| SCHEMBL27910100 | 0.75 | ALDH1A1 (0.67) | LMNAALDH1A1NPSR1HPGDHTT | |
| SCHEMBL17064454 | 0.75 | CRHBP (0.70) | LMNAALDH1A1HTTSMN1; SMN2PKM | |
| SCHEMBL27927859 | 0.75 | ALDH1A1 (0.74) | LMNAALDH1A1NPSR1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106718-A | Heat resistant relief structures | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0364949-A2 | Heat-stable positive photoresist | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |