Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524569 | 0.82 | SLC6A11 (0.47) | KIF11CNR1CNR2CASRNPC1 | |
| SCHEMBL4421178 | 0.70 | HDAC6 (0.47) | ALDH1A1HPGDSMN1; SMN2KMT2AHDAC3 | |
| SCHEMBL3700787 | 0.70 | L3MBTL1 (0.47) | CASRNPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14315813 | 0.67 | ALDH1A1 (0.50) | CNR1ALDH1A1SMN1; SMN2MTNR1A | |
| SCHEMBL3689532 | 0.67 | MTNR1B (0.43) | KIF11NPC1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL14762445 | 0.65 | SMN1; SMN2 (0.45) | KIF11CASRNPC1ALDH1A1HPGD | |
| SCHEMBL3695475 | 0.65 | SLC6A11 (0.43) | KIF11KMT2A | |
| SCHEMBL3698291 | 0.65 | SLC6A11 (0.43) | KIF11KMT2A | |
| SCHEMBL21596070 | 0.65 | MTNR1A (0.75) | NPC1ALDH1A1SMN1; SMN2MAPTMTNR1A | |
| SCHEMBL3357892 | 0.65 | CASR (0.54) | CASRNPC1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909020-A | Lipids and compositions for delivery of therapeutic agents | 阿布特斯生物制药公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-111808084-A | Novel lipids and compositions for delivery of therapeutic agents | 阿布特斯生物制药公司 | 2020-10-23 | — | — | CN | disclosed |