Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850244 | 0.85 | MALT1 (0.51) | MALT1MAPTKDM4EMETAXL | |
| SCHEMBL2858340 | 0.85 | MALT1 (0.42) | MALT1PHGDH | |
| SCHEMBL2856635 | 0.83 | MALT1 (0.42) | MALT1KDM4EPHGDHALDH1A1 | |
| SCHEMBL2850882 | 0.81 | MALT1 (0.44) | MALT1PHGDH | |
| SCHEMBL2858606 | 0.80 | P2RY1 (0.47) | P2RY1MAPTGAAKDM4EMET | |
| SCHEMBL2855275 | 0.79 | MAPT (0.45) | P2RY1MAPTGAAKDM4ETRPV1 | |
| SCHEMBL2859870 | 0.76 | TLR7 (0.38) | P2RY1MAPTGAAKDM4EMET | |
| SCHEMBL2856517 | 0.76 | MAPT (0.42) | P2RY1MAPTGAAKDM4EMET | |
| SCHEMBL2861646 | 0.76 | NPC1 (0.42) | P2RY1MAPTGAAKDM4E | |
| SCHEMBL2853088 | 0.76 | NR3C1 (0.41) | P2RY1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |