Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 15/20 | 0.39 |
| ▸ | IL17A | Q16552 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142433 | 0.88 | TSHR (0.46) | SCN9AMEN1KMT2ATSHR | |
| SCHEMBL28513653 | 0.83 | SYK (0.51) | RORCMEN1KMT2ATSHR | |
| SCHEMBL21815478 | 0.79 | MEN1 (0.47) | MEN1KMT2ATSHR | |
| SCHEMBL3918082 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL27208962 | 0.76 | MAPT (0.40) | MEN1KMT2ATSHR | |
| SCHEMBL28941585 | 0.75 | SCN9A (0.38) | SCN9AMEN1KMT2ATSHR | |
| SCHEMBL10196592 | 0.74 | ACHE (0.49) | MEN1KMT2AXDH | |
| SCHEMBL20206745 | 0.74 | GRM2 (0.47) | SCN9ARORCDHFRDCPS | |
| SCHEMBL28536772 | 0.74 | L3MBTL1 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL3649899 | 0.73 | MCOLN3 (0.50) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074522-B | Compounds as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | 深圳信立泰药业股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-112074522-A | Compounds as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | 深圳信立泰药业股份有限公司 | 2020-12-11 | — | — | CN | disclosed |