Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.42 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853595 | 0.91 | LMNA (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL2861572 | 0.90 | CA1 (0.49) | CA1CA2CA12CA9 | |
| SCHEMBL2852372 | 0.89 | MAPT (0.48) | CA1CA2CA12CA9LMNA | |
| SCHEMBL2856585 | 0.87 | CA1 (0.44) | CA1CA2CA12CA9 | |
| SCHEMBL2861646 | 0.86 | NPC1 (0.42) | RIPK1 | |
| SCHEMBL2850733 | 0.86 | KEAP1 (0.46) | CA1CA2CA12CA9 | |
| SCHEMBL2856867 | 0.85 | NPC1 (0.53) | LMNASMN1; SMN2 | |
| SCHEMBL2856588 | 0.82 | KEAP1 (0.42) | CA1CA2CA12CA9LMNA | |
| SCHEMBL2859362 | 0.82 | P2RX1 (0.48) | KDR | |
| SCHEMBL2856385 | 0.81 | CCR1 (0.44) | CA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |