Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17779609 | 0.76 | MAPT (0.41) | NAMPTKMT2AMEN1NR1H4RAB9A | |
| SCHEMBL20786981 | 0.69 | MITF (0.42) | KMT2AMEN1RAB9AHDAC1HDAC8 | |
| SCHEMBL24379800 | 0.68 | MEN1 (0.54) | TDP1KMT2AMEN1NR1H4RAB9A | |
| SCHEMBL21138155 | 0.66 | EP300 (0.48) | KMT2AMEN1RAB9AHDAC1HDAC8 | |
| SCHEMBL20787640 | 0.66 | NPC1 (0.49) | TDP1KMT2AMEN1RAB9ATP53 | |
| SCHEMBL26543681 | 0.65 | PLG (0.38) | TDP1KMT2AMEN1RAB9AHDAC1 | |
| SCHEMBL24379797 | 0.65 | EP300 (0.53) | TDP1KMT2AMEN1NR1H4RAB9A | |
| SCHEMBL22461618 | 0.65 | NAMPT (0.65) | NAMPTKMT2AMEN1NR1H4RAB9A | |
| SCHEMBL17526122 | 0.65 | NAMPT (0.73) | NAMPTKMT2AMEN1RAB9AHDAC8 | |
| SCHEMBL22461360 | 0.65 | NAMPT (0.65) | NAMPTKMT2AMEN1NR1H4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793424-B | Ascomycetes amides | 亥姆霍兹感染研究中心有限公司 | 2021-02-19 | — | — | CN | disclosed |