Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860106 | 0.94 | KLKB1 (0.52) | KLKB1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL2848515 | 0.90 | LMNA (0.50) | KLKB1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2859353 | 0.89 | TAAR1 (0.66) | TAAR1HSD17B10NPC1RAB9APLAAT3 | |
| SCHEMBL2861622 | 0.85 | EPHX1 (0.60) | L3MBTL1HTTSMN1; SMN2HPGD | |
| SCHEMBL2853080 | 0.85 | LMNA (0.50) | KLKB1NPC1RAB9APOLBTDP1 | |
| SCHEMBL2852519 | 0.82 | TAAR1 (0.59) | KLKB1TAAR1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2859721 | 0.82 | KLKB1 (0.49) | KLKB1RAB9AL3MBTL1ALDH1A1HTT | |
| SCHEMBL2860989 | 0.81 | ALDH1A1 (0.68) | NPC1RAB9APOLBALDH1A1HTT | |
| SCHEMBL2854712 | 0.80 | TAAR1 (0.54) | KLKB1TAAR1NPC1RAB9APOLB | |
| SCHEMBL2854565 | 0.80 | KLKB1 (0.75) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |