Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860106 | 0.91 | KLKB1 (0.52) | EPHX1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2852927 | 0.85 | KLKB1 (0.50) | L3MBTL1HTTHPGDSMN1; SMN2 | |
| SCHEMBL2848515 | 0.84 | LMNA (0.50) | LMNAHPGDSMN1; SMN2FAAH | |
| SCHEMBL3430736 | 0.83 | EPHX1 (0.79) | EPHX1NAMPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29881595 | 0.83 | EPHX1 (0.79) | EPHX1NAMPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2853080 | 0.82 | LMNA (0.50) | L3MBTL1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL2852519 | 0.81 | TAAR1 (0.59) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL2859721 | 0.81 | KLKB1 (0.49) | L3MBTL1HTTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL2860989 | 0.78 | ALDH1A1 (0.68) | HTTHPGDSMN1; SMN2FAAH | |
| SCHEMBL27687099 | 0.78 | EPHX1 (0.70) | EPHX1NAMPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |