Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860106 | 0.84 | KLKB1 (0.52) | ALDH1A1SMN1; SMN2RAB9ANPC1SCD5 | |
| SCHEMBL9371939 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HTTSMN1; SMN2HPGDRAB9A | |
| SCHEMBL2852927 | 0.81 | KLKB1 (0.50) | ALDH1A1HTTSMN1; SMN2HPGDRAB9A | |
| SCHEMBL2848515 | 0.80 | LMNA (0.50) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL2861622 | 0.78 | EPHX1 (0.60) | HTTSMN1; SMN2HPGDFAAH | |
| SCHEMBL2853080 | 0.78 | LMNA (0.50) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL2859721 | 0.77 | KLKB1 (0.49) | ALDH1A1HTTSMN1; SMN2HPGDRAB9A | |
| SCHEMBL2852519 | 0.75 | TAAR1 (0.59) | ALDH1A1SMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL2848480 | 0.74 | ALDH1A1 (0.61) | ALDH1A1HTTSMN1; SMN2HPGDRAB9A | |
| SCHEMBL2859353 | 0.73 | TAAR1 (0.66) | ALDH1A1HTTSMN1; SMN2HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |