Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858580 | 0.91 | HIF1A (0.43) | MAPTTP53 | |
| SCHEMBL2857468 | 0.85 | MAPT (0.47) | MAPTTP53HPGDALDH1A1L3MBTL1 | |
| SCHEMBL2850323 | 0.84 | MAPT (0.47) | MTNR1AMTNR1BMAPTTP53MEN1 | |
| SCHEMBL2853261 | 0.83 | SPR (0.48) | MAPTTP53ALDH1A1 | |
| SCHEMBL2854625 | 0.82 | POLB (0.48) | TP53HPGDALDH1A1 | |
| SCHEMBL2858680 | 0.82 | NPC1 (0.45) | MAPTTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2861634 | 0.82 | RAB9A (0.44) | MAPTTP53CRHBPCRHR2HPGD | |
| SCHEMBL2854716 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BMAPTTP53MEN1 | |
| SCHEMBL2850369 | 0.81 | P2RX7 (0.56) | MAPTTP53 | |
| SCHEMBL2854313 | 0.81 | NPSR1 (0.54) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |