Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863134 | 0.94 | CCR1 (0.48) | FAAHMAPTRORCALDH1A1CCR1 | |
| SCHEMBL2854531 | 0.90 | LMNA (0.52) | LMNAPOLBMAPTTP53MEN1 | |
| SCHEMBL2860234 | 0.89 | HPGD (0.54) | GAAPOLBMAPTTP53MEN1 | |
| SCHEMBL2857180 | 0.88 | NPSR1 (0.53) | GAAPOLBMAPTTP53CCR1 | |
| SCHEMBL2853267 | 0.88 | HPGD (0.55) | LMNAFAAHMAPTTP53ALDH1A1 | |
| SCHEMBL2853344 | 0.88 | HPGD (0.55) | LMNAMAPTTP53MEN1KMT2A | |
| SCHEMBL2860466 | 0.87 | RCE1 (0.47) | LMNARCE1GAAFAAHPOLB | |
| SCHEMBL2857338 | 0.84 | RAB9A (0.47) | LMNAGAAFAAHPOLBMAPT | |
| SCHEMBL2852238 | 0.84 | GAA (0.55) | GAATHRBTP53MEN1KMT2A | |
| SCHEMBL2855676 | 0.83 | CCR1 (0.63) | RCE1GAAPOLBMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |