Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 14/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856635 | 0.90 | MALT1 (0.42) | MALT1PHGDH | |
| SCHEMBL2850882 | 0.86 | MALT1 (0.44) | MALT1PHGDH | |
| SCHEMBL2853326 | 0.85 | MALT1 (0.39) | MALT1PHGDH | |
| SCHEMBL2855927 | 0.82 | MALT1 (0.57) | MALT1 | |
| SCHEMBL2854678 | 0.78 | ATR (0.40) | — | |
| SCHEMBL2857444 | 0.76 | ALDH1A1 (0.42) | MALT1KMT2A | |
| SCHEMBL2853241 | 0.76 | SMN1; SMN2 (0.41) | KMT2A | |
| SCHEMBL2861607 | 0.76 | TRPV1 (0.42) | KMT2A | |
| SCHEMBL2857337 | 0.76 | KMT2A (0.43) | MALT1HSP90AA1KMT2A | |
| SCHEMBL2850388 | 0.75 | LMNA (0.35) | MALT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |