SCHEMBL523288

SCHEMBL523288

C[Si](C)(Cl)CCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
SIGMAR1 Q99720 4/20 0.45
MAOA P21397 1/20 0.45
CHRM2 P08172 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KCNH2 Q12809 1/20 0.44
AOC3 Q16853 1/20 0.44
MAOB P27338 1/20 0.43
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5654858 0.94 L3MBTL1 (0.48) L3MBTL1MEN1KMT2ASIGMAR1MAOA
SCHEMBL16207822 0.92 SIGMAR1 (0.50) L3MBTL1SIGMAR1MAOAMAOB
SCHEMBL28731916 0.92 SIGMAR1 (0.50) L3MBTL1SIGMAR1MAOAMAOB
SCHEMBL524107 0.87 L3MBTL1 (0.45) L3MBTL1MEN1KMT2ASIGMAR1MAOA
SCHEMBL523595 0.86 TDP1 (0.48) MAOAHTR1AADRA2ASLC6A2ADRA1A
SCHEMBL17444453 0.84 PPARG (0.42) MEN1KMT2AMAOAMAOB
SCHEMBL1599233 0.82 SIGMAR1 (0.48) L3MBTL1SIGMAR1MAOAADRA1ASLC6A3
SCHEMBL16216219 0.82 L3MBTL1 (0.48) L3MBTL1MEN1KMT2ASIGMAR1MAOA
SCHEMBL30599803 0.82 SIGMAR1 (0.48) L3MBTL1SIGMAR1MAOAADRA1ASLC6A3
SCHEMBL30599804 0.82 SIGMAR1 (0.48) L3MBTL1SIGMAR1MAOAADRA1ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120712-B High-permeability thermoplastic epoxy resin composition and application thereof 广东盈骅新材料科技有限公司 2024-08-09 CN claimed
CN-114341072-B Textured glass articles and methods of making the same 康宁股份有限公司 2023-11-14 CN claimed
CN-116120712-A High-permeability thermoplastic epoxy resin composition and application thereof 广东盈骅新材料科技有限公司 2023-05-16 CN claimed
CN-115748258-A Novel environment-friendly antibacterial deodorizing finishing agent and preparation method thereof 广东湛丰精细化工有限公司 2023-03-07 CN claimed
US-11485677-B2 Textured glass articles and methods of making the same CORNING INCORPORATED (US) 2022-11-01 US claimed
CN-114341072-A Textured glass article and method of making same 康宁股份有限公司 2022-04-12 CN claimed
US-20200407270-A1 TEXTURED GLASS ARTICLES AND METHODS OF MAKING THE SAME CORNING INCORPORATED 2020-12-31 US claimed
WO-2020264232-A2 TEXTURED GLASS ARTICLES AND METHODS OF MAKING THE SAME CORNING INCORPORATED (US) 2020-12-30 WO claimed
CN-104262515-B A kind of granular random/stereoblock polystyrene preparation method 沈阳化工大学 2017-08-08 CN claimed
CN-105080492-B One kind separation alkali compounds silica gel chromatographic column filling material and preparation method thereof 浙江月旭材料科技有限公司 2017-07-11 CN claimed
CN-105080492-A Silica gel chromatographic packing for separation of alkaline compound and preparation method of silica gel chromatographic packing ZHEJIANG YUEXU MATERIAL TECHNOLOGY CO LTD 2015-11-25 CN claimed
WO-2010113188-A1 FLUORURATED SILICONIC POLYMER, SYNTHESIS METHOD AND USE MAFLON S.R.L. (IT) 2010-10-07 WO claimed
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
US-5734043-A POLYSACCHARIDE SUPPORTED ON SILICA GEL DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-31 US claimed
EP-4083046-B1 METHOD FOR PREPARING HALOSILANE COMPOUNDS SHINETSU CHEMICAL CO (JP) 2025-03-26 EP disclosed
US-12109812-B2 Ink jet printing method and ink jet printing apparatus SEIKO EPSON CORPORATION (JP) 2024-10-08 US disclosed
WO-1990001565-A1 SEPARATION AND PURIFICATION OF BRANCHED BETA CYCLODEXTRINS AMERICAN MAIZE-PRODUCTS COMPANY (US) 1990-02-22 WO disclosed
US-4808232-A COMPLEXING WITH AN INCLUSION COMPOUND-SPACER-MATRIX AND ELUTING AMERICAN MAIZE-PRODUCTS COMPANY (US) 1989-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 L3MBTL1 3521/4885MEN1 314/4885KMT2A 738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.