Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190616 | 0.76 | SMYD3 (0.50) | P2RX7GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4143337 | 0.72 | GAA (0.45) | P2RX7ALOX5APGAAMEN1KMT2A | |
| SCHEMBL15559049 | 0.71 | CRHR1 (0.49) | P2RX7GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL738587 | 0.69 | P2RX7 (0.71) | P2RX7GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL1987660 | 0.68 | TAS1R3 (0.64) | P2RX7GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL18887343 | 0.67 | ABL1 (0.68) | ALOX5APGAAKDR | |
| SCHEMBL3172457 | 0.66 | TAS1R3 (0.59) | P2RX7GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL27634155 | 0.66 | P2RX7 (0.54) | P2RX7GAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3165934 | 0.64 | TAS1R3 (0.67) | P2RX7ALDH1A1NPC1RAB9A | |
| SCHEMBL14688259 | 0.64 | TAS1R3 (0.62) | P2RX7SMN1; SMN2CNR1CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635970-B | Benzimidazolone and benzothiazolone compounds and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-03-12 | — | — | CN | disclosed |