Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566911 | 0.80 | HTR6 (0.50) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL777153 | 0.80 | HTR6 (0.50) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL14566913 | 0.78 | HTR6 (0.48) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL5664875 | 0.78 | HTR6 (0.48) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL775525 | 0.76 | HTR6 (0.46) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL18986850 | 0.76 | ALDH1A1 (0.48) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL6053237 | 0.76 | HSD11B1 (0.47) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL776228 | 0.76 | HTR6 (0.46) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL5961978 | 0.76 | HTR6 (0.46) | HTR6APOBEC3GCA1CA2CA5A | |
| SCHEMBL2991893 | 0.74 | HTR6 (0.44) | HTR6APOBEC3GCA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116911-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20230272002-A1 | PHOTOREDOX PROTEIN MODIFICATION | THE ROSALIND FRANKLIN INSTITUTE (GB) | 2023-08-31 | — | — | US | disclosed |
| US-20230272002-A1 | PHOTOREDOX PROTEIN MODIFICATION | THE ROSALIND FRANKLIN INSTITUTE (GB) | 2023-08-31 | — | — | US | disclosed |
| CN-107162928-B | Halogenated analogs of anti-fibrotic agents | 塞尔塔医疗有限公司 | 2022-03-11 | — | — | CN | disclosed |
| WO-2022013564-A1 | PHOTOREDOX PROTEIN MODIFICATION | THE ROSALIND FRANKLIN INSTITUTE (GB) | 2022-01-20 | — | — | WO | disclosed |
| CN-112047839-B | 1-iodine-3-perfluoroalkyl alkene compound and preparation method thereof | 中山大学 | 2021-11-05 | — | — | CN | disclosed |
| CN-112047839-A | 1-iodine-3-perfluoroalkyl alkene compound and preparation method thereof | 中山大学 | 2020-12-08 | — | — | CN | disclosed |
| US-20180016227-A1 | PROCESS FOR THE SYNTHESIS OF DIFLUOROMETHYL ETHER-BASED COMPOUNDS | TRILLIUM THERAPEUTICS INC. (CA) | 2018-01-18 | — | — | US | disclosed |
| US-20180016227-A1 | PROCESS FOR THE SYNTHESIS OF DIFLUOROMETHYL ETHER-BASED COMPOUNDS | TRILLIUM THERAPEUTICS INC. (CA) | 2018-01-18 | — | — | US | disclosed |
| WO-2016123707-A1 | PROCESS FOR THE SYNTHESIS OF DIFLUOROMETHYL ETHER-BASED COMPOUNDS | TRILLIUM THERAPEUTICS INC. (CA) | 2016-08-11 | — | — | WO | disclosed |
| EP-1963277-B1 | FLUORINATED COMPOUNDS | NPS PHARMA INC (US) | 2010-01-20 | — | — | EP | disclosed |
| EP-2099444-A1 | USE OF D-SERINE DERIVATIVES FOR THE TREATMENT OF ANXIETY DISORDERS | NPS PHARMACEUTICALS, INC. (CA) | 2009-09-16 | — | — | EP | disclosed |
| US-20090005433-A1 | Fluorinated Compounds | NPS PHARMACEUTICALS, INC. | 2009-01-01 | — | — | US | disclosed |
| US-20090005433-A1 | Fluorinated Compounds | NPS PHARMACEUTICALS, INC. | 2009-01-01 | — | — | US | disclosed |
| EP-1963277-A1 | FLUORINATED COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2008070994-A1 | USE OF D-SERINE DERIVATIVES FOR THE TREATMENT OF ANXIETY DISORDERS | NPS PHARMACEUTICALS, INC. (CA) | 2008-06-19 | — | — | WO | disclosed |
| WO-2007076306-A1 | FLUORINATED COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| US-7119232-B2 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-10-10 | — | — | US | disclosed |
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | UNIVERSITY OF SOUTHERN CALIFORNIA | 2006-03-09 | — | — | US | disclosed |
| WO-2005097739-A2 | NUCLEOPHILIC SUBSTITUTION REACTIONS OF DIFLUOROMETHYL PHENYL SULFONE WITH ALKYL HALIDES LEADING TO THE FACILE SYNTHESIS OF TERMINAL 1,1-DIFLUORO-1-ALKENES AND DIFLUOROMETHYLALKANES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230272002-A1 | PHOTOREDOX PROTEIN MODIFICATION | PPOX, CACYBP, BRI3BP | HTR6 4672/4885APOBEC3G 3106/4885CA1 1284/4885 |
| US-20180016227-A1 | PROCESS FOR THE SYNTHESIS OF DIFLUOROMETHYL ETHER-BASED COMPOUNDS | CYP2F1, CYP2E1, PAH | HTR6 2361/4885APOBEC3G 2214/4885CA1 4014/4885 |
| US-20090005433-A1 | Fluorinated Compounds | CNR1, NPFFR1, AFF1 | HTR6 1124/4885APOBEC3G 4294/4885CA1 2396/4885 |
| US-20260116911-A1 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SCN4A, CACNG4, SLC6A4 | HTR6 237/4885APOBEC3G 4211/4885CA1 737/4885 |
| US-20060052643-A1 | Nucleophilic substitution reactions of difluorormethyl phenyl sulfone with alkyl halides leading to the facile synthesis of terminal 1,1-difluoro-1-alkenes and difluoromethylalkanes | PFAS, FRK, PFKFB1 | HTR6 2603/4885APOBEC3G 1152/4885CA1 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.