Glycolic Acid

Glycolic Acid

SCHEMBL28544338

O=C([O-])CO.O=C([O-])CO.O=C([O-])CO.O=C([O-])CO.[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Glycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA4 known ✓ P22748 5/20 0.57
CA1 known ✓ P00915 3/20 0.43
CA2 known ✓ P00918 1/20 0.42
CASP1 P29466 1/20 0.53
FAHD1 Q6P587 1/20 0.46
FFAR3 O14843 2/20 0.44
HDAC3 O15379 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
OR51E2 Q9H255 1/20 0.44
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.38
LDHA P00338 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL47925 1.00
Glycolic Acid SCHEMBL16874984 1.00 CA4 (0.57) CA4CASP1FAHD1FFAR3HDAC3
Glycolic Acid SCHEMBL2907528 1.00 CA4 (0.57) CA4CASP1FAHD1FFAR3HDAC3
Glycolic Acid SCHEMBL1165244 0.96
Glycolic Acid SCHEMBL8372063 0.96 CA4 (0.53) CA4CASP1FAHD1FFAR3HDAC3
Glycolic Acid SCHEMBL16029754 0.96 CA4 (0.54) CA4CASP1FAHD1FFAR3HDAC3
Glycolic Acid SCHEMBL9053898 0.96
Glycolic Acid SCHEMBL9053896 0.96 CA4 (0.53) CA4CASP1FAHD1FFAR3HDAC3
Glycolic Acid SCHEMBL16029747 0.96 CA4 (0.53) CA4CASP1FAHD1FFAR3HDAC3
Glycolic Acid SCHEMBL10804581 0.96 CA4 (0.53) CA4CASP1FAHD1FFAR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110022842-B Solid soap composition containing microemulsion 三得利控股株式会社 2022-03-15 CN disclosed
CN-108350400-B Laundry washing method, use of polypeptides and detergent compositions 诺维信公司 2021-03-30 CN disclosed