Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858618 | 0.93 | ALDH1A1 (0.41) | P2RX7TRPV1CCR1ALDH1A1KDM4E | |
| SCHEMBL2854705 | 0.92 | ALDH1A1 (0.46) | P2RX7TRPV1ALDH1A1KDM4EMAPT | |
| SCHEMBL2848315 | 0.90 | TRPV1 (0.54) | P2RX7TRPV1ALDH1A1KDM4EMAPT | |
| SCHEMBL2853063 | 0.90 | P2RX7 (0.48) | P2RX7TRPV1CCR1ALDH1A1KDM4E | |
| SCHEMBL2857996 | 0.86 | CCR1 (0.48) | P2RX7TRPV1CCR1ALDH1A1KDM4E | |
| SCHEMBL2863154 | 0.86 | MAPT (0.45) | P2RX7CCR1ALDH1A1KDM4EMAPT | |
| SCHEMBL2853186 | 0.85 | TRPV1 (0.41) | P2RX7TRPV1KDM4EMAPTNPSR1 | |
| SCHEMBL2860458 | 0.85 | TP53 (0.46) | P2RX7MAPTNR3C1NPSR1 | |
| SCHEMBL2850857 | 0.85 | TP53 (0.46) | P2RX7MAPTNR3C1NPSR1 | |
| SCHEMBL2854346 | 0.85 | MAPT (0.52) | P2RX7CCR1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |