Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852526 | 0.85 | ATF1 (0.42) | SMN1; SMN2CNR2ALDH1A1MAPT | |
| SCHEMBL2860252 | 0.84 | MAPT (0.39) | SMN1; SMN2TSHRKMT2AMAPTLMNA | |
| SCHEMBL2850712 | 0.83 | MAPT (0.41) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL2854992 | 0.83 | L3MBTL1 (0.43) | RAB9ASMN1; SMN2NPC1TP53TSHR | |
| SCHEMBL2852244 | 0.82 | MAPT (0.48) | SMN1; SMN2KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2850809 | 0.82 | MAPT (0.43) | RAB9ASMN1; SMN2TP53TSHRKMT2A | |
| SCHEMBL2858283 | 0.82 | MAPT (0.43) | RAB9ASMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL2859478 | 0.82 | ALDH1A1 (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL2857582 | 0.81 | MAPT (0.42) | RAB9ASMN1; SMN2NPC1TP53KMT2A | |
| SCHEMBL2853465 | 0.81 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |