Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852353 | 0.92 | RAB9A (0.44) | RAB9AMAPTALDH1A1SMN1; SMN2TRPC1 | |
| SCHEMBL2857582 | 0.90 | MAPT (0.42) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2859508 | 0.89 | CYP1A2 (0.46) | RAB9ANPC1MAPTHPGDALDH1A1 | |
| SCHEMBL2858283 | 0.89 | MAPT (0.43) | RAB9AMAPTALDH1A1SMN1; SMN2TRPC1 | |
| SCHEMBL2850809 | 0.89 | MAPT (0.43) | RAB9AMAPTALDH1A1SMN1; SMN2TRPC1 | |
| SCHEMBL2854533 | 0.87 | MEN1 (0.46) | RAB9ANPC1MAPTSMN1; SMN2TRPC1 | |
| SCHEMBL2852121 | 0.86 | P2RX7 (0.43) | RAB9AMAPTSMN1; SMN2TRPC1TRPC3 | |
| SCHEMBL2853258 | 0.85 | NPY5R (0.45) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL2850337 | 0.85 | MAPT (0.40) | MAPTGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL2850701 | 0.84 | MAPT (0.39) | RAB9AMAPTALDH1A1SMN1; SMN2TRPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |