Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852552 | 0.87 | MEN1 (0.51) | KDM4EALDH1A1MAPTPDK1PDK2 | |
| SCHEMBL2848541 | 0.86 | RAB9A (0.43) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854596 | 0.86 | TP53 (0.46) | KDM4EALDH1A1GAAMAPTPOLB | |
| SCHEMBL2859508 | 0.85 | CYP1A2 (0.46) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2855775 | 0.84 | P2RY1 (0.44) | KDM4EALDH1A1GAAMAPTPOLB | |
| SCHEMBL2850610 | 0.83 | MAPT (0.40) | KDM4EALDH1A1GAAMAPTPDK2 | |
| SCHEMBL2852548 | 0.83 | MAPT (0.37) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2857074 | 0.83 | LPAR1 (0.42) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2854497 | 0.83 | NPY5R (0.44) | KDM4EALDH1A1GAAMAPTPOLB | |
| SCHEMBL2848317 | 0.83 | MAPT (0.46) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |