Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850369 | 0.92 | P2RX7 (0.56) | P2RX7TP53MAPT | |
| SCHEMBL2853335 | 0.91 | TP53 (0.48) | P2RX7TP53MAPTTHRBNPC1 | |
| SCHEMBL2856602 | 0.89 | RIPK1 (0.46) | P2RX7TP53MAPTHPGD | |
| SCHEMBL2858157 | 0.87 | POLB (0.55) | P2RX7HPGDLMNANPC1RAB9A | |
| SCHEMBL2861261 | 0.85 | HPGD (0.64) | MAPTHPGDLMNANPC1RAB9A | |
| SCHEMBL2852334 | 0.84 | HPGD (0.55) | TP53MAPTHPGDLMNANPC1 | |
| SCHEMBL2858313 | 0.84 | P2RX7 (0.56) | P2RX7MAPTHPGDLMNANPC1 | |
| SCHEMBL2858268 | 0.84 | P2RX7 (0.48) | P2RX7TP53MAPTHPGDLMNA | |
| SCHEMBL2858680 | 0.81 | NPC1 (0.45) | P2RX7TP53MAPTNPC1RAB9A | |
| SCHEMBL2854815 | 0.81 | MEN1 (0.50) | MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |