Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180249 | 0.79 | PTGES (0.43) | PTGESTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28551500 | 0.79 | TERT (0.51) | PTGESTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29180242 | 0.78 | PTGES (0.57) | PTGESTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21801095 | 0.78 | TDP1 (0.64) | TDP1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28045620 | 0.76 | PTGES (0.75) | PTGESTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29180243 | 0.75 | PTGES (0.39) | PTGESTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29180248 | 0.74 | PTGES (0.47) | PTGESTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28548041 | 0.73 | ESR1 (0.57) | PTGESKDM4ETNKSPOLBCYP3A4 | |
| SCHEMBL20953928 | 0.71 | SHBG (0.59) | PTGESTDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15775390 | 0.69 | TNKS (0.46) | PTGESTDP1KDM4ETNKSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-A | Flavone compounds for treating and preventing hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2021-04-02 | — | — | CN | disclosed |