Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548525 | 0.79 | PTGES (0.51) | PTGESESR1ESR2SMN1; SMN2CYP3A4 | |
| SCHEMBL21801314 | 0.79 | CSNK2A2 (0.56) | ESR1ESR2SMN1; SMN2CYP3A4HPGD | |
| SCHEMBL29180243 | 0.79 | PTGES (0.39) | PTGESESR1ESR2SMN1; SMN2CYP3A4 | |
| SCHEMBL28551500 | 0.74 | TERT (0.51) | PTGESESR1ESR2SMN1; SMN2CYP3A4 | |
| SCHEMBL29180241 | 0.73 | PRKAB2 (0.39) | PTGESESR1ESR2SMN1; SMN2CYP3A4 | |
| SCHEMBL29180242 | 0.72 | PTGES (0.57) | PTGESESR1ESR2SMN1; SMN2CYP3A4 | |
| SCHEMBL5085541 | 0.71 | ERAP1 (0.47) | ESR1ESR2HPGDKDM4EMAPK1 | |
| SCHEMBL24046928 | 0.70 | CSNK2A2 (0.65) | ESR1ESR2SMN1; SMN2CYP3A4HPGD | |
| SCHEMBL20953928 | 0.69 | SHBG (0.59) | PTGESESR1ESR2SMN1; SMN2CYP3A4 | |
| SCHEMBL28548041 | 0.69 | ESR1 (0.57) | PTGESESR1ESR2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |