Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775344 | 0.87 | MAOA (0.57) | TNKSMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15775643 | 0.86 | MAOB (0.46) | TNKSMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15775345 | 0.83 | ALDH1A1 (0.59) | TNKSMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15775766 | 0.73 | PARP1 (0.63) | TNKSKMT2AALDH1A1TDP1PARP1 | |
| SCHEMBL5067323 | 0.70 | TDP1 (0.49) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5311674 | 0.69 | GABRP (0.56) | TNKSMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28548525 | 0.69 | PTGES (0.51) | TNKSMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28276841 | 0.68 | PTGES (0.67) | TNKSMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3364130 | 0.67 | GPR35 (0.52) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL29461466 | 0.67 | PTGES (0.53) | TNKSMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |