Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180242 | 0.81 | PTGES (0.57) | PTGESCYP3A4KMT2AHPGDMAPT | |
| SCHEMBL29180243 | 0.76 | PTGES (0.39) | PTGESCYP3A4KMT2AHPGDMAPT | |
| SCHEMBL28548525 | 0.74 | PTGES (0.51) | PTGESCYP3A4KMT2AHPGDMAPT | |
| SCHEMBL29180249 | 0.67 | PTGES (0.43) | PTGESCYP3A4KMT2AHPGDMAPT | |
| SCHEMBL28551500 | 0.66 | TERT (0.51) | PTGESCYP3A4KMT2AHPGDMAPT | |
| SCHEMBL28537645 | 0.66 | CEL (0.37) | — | |
| SCHEMBL23230944 | 0.63 | HSD17B10 (0.50) | ESR1ESR2HSD17B10TTR | |
| SCHEMBL30249939 | 0.63 | HSD17B10 (0.50) | ESR1ESR2HSD17B10TTR | |
| SCHEMBL21801095 | 0.62 | TDP1 (0.64) | CYP3A4KMT2AHPGDMAPTMAPK1 | |
| SCHEMBL20953928 | 0.62 | SHBG (0.59) | PTGESCYP3A4HPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |