Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852350 | 0.92 | NPC1 (0.53) | HPGDNPC1RAB9ANR3C1 | |
| SCHEMBL2856862 | 0.92 | NPC1 (0.53) | HRH3ASAH1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2857176 | 0.86 | ALDH1A1 (0.46) | FAAHMGLLASAH1RAB9A | |
| SCHEMBL2861261 | 0.85 | HPGD (0.64) | HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2859872 | 0.85 | TAAR1 (0.54) | HPGDNPC1RAB9ASMN1; SMN2NR3C1 | |
| SCHEMBL2850598 | 0.84 | KDM4E (0.47) | FAAHMGLLASAH1SMN1; SMN2 | |
| SCHEMBL2853389 | 0.84 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2861634 | 0.82 | RAB9A (0.44) | HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2856602 | 0.81 | RIPK1 (0.46) | HPGD | |
| SCHEMBL2860099 | 0.80 | TAAR1 (0.46) | ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |