Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850323 | 0.91 | MAPT (0.47) | RAB9ANPC1PKMTAAR1ALDH1A1 | |
| SCHEMBL2857276 | 0.89 | RAB9A (0.47) | RAB9ANPC1PKMHPGDMAPK1 | |
| SCHEMBL2856602 | 0.89 | RIPK1 (0.46) | HPGDMAPK1MAPTTP53 | |
| SCHEMBL2852350 | 0.87 | NPC1 (0.53) | RAB9ANPC1HPGDMAPK1TAAR1 | |
| SCHEMBL2861640 | 0.87 | ALDH1A1 (0.45) | RAB9APKMMAPK1ALDH1A1MAPT | |
| SCHEMBL2860131 | 0.86 | ALDH1A1 (0.46) | HPGDTAAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2854704 | 0.83 | P2RX7 (0.48) | PKMHPGDMAPK1ALDH1A1MAPT | |
| SCHEMBL2858580 | 0.83 | HIF1A (0.43) | RAB9ANPC1MAPK1TAAR1MAPT | |
| SCHEMBL2859872 | 0.83 | TAAR1 (0.54) | RAB9ANPC1HPGDTAAR1ALDH1A1 | |
| SCHEMBL2854887 | 0.82 | HPGD (0.49) | RAB9ANPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |