Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855213 | 1.00 | ITGB3 (0.51) | ITGB3ITGA2BP2RX7ALDH1A1KDM4E | |
| SCHEMBL2861260 | 0.91 | ALDH1A1 (0.56) | ITGB3ITGA2BP2RX7ALDH1A1KDM4E | |
| SCHEMBL2419128 | 0.91 | ALDH1A1 (0.56) | ITGB3ITGA2BP2RX7ALDH1A1KDM4E | |
| SCHEMBL30229545 | 0.91 | ALDH1A1 (0.54) | ITGB3ITGA2BP2RX7ALDH1A1KDM4E | |
| SCHEMBL1828085 | 0.90 | CTSL (0.51) | ITGB3ITGA2BP2RX7ALDH1A1CTSL | |
| SCHEMBL1828087 | 0.90 | CTSL (0.51) | ITGB3ITGA2BP2RX7ALDH1A1CTSL | |
| SCHEMBL2866584 | 0.89 | P2RX7 (0.53) | ITGB3ITGA2BP2RX7ALDH1A1KDM4E | |
| SCHEMBL2866586 | 0.89 | P2RX7 (0.53) | ITGB3ITGA2BP2RX7ALDH1A1KDM4E | |
| SCHEMBL15020052 | 0.88 | ITGB3 (0.61) | ITGB3ITGA2BP2RX7ALDH1A1KDM4E | |
| SCHEMBL7318182 | 0.88 | ITGB3 (0.61) | ITGB3ITGA2BP2RX7ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346971-B1 | Production method for biarylalanine | SUMITOMO CHEMICAL CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-7091373-B2 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| US-20040024229-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-02-05 | — | — | US | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024229-A1 | Production method for biarylalanine | BCAT2, BCAT1, PAH | ITGB3 4101/4885ITGA2B 4475/4885P2RX7 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.