Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.41 |
| ▸ | MMP9 | P14780 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529608 | 0.72 | LMNA (0.45) | ALDH1A1LMNAKDM4EKEAP1NFE2L2 | |
| SCHEMBL1628645 | 0.71 | HPGD (0.35) | ALDH1A1LMNAKDM4EKMT2AHTT | |
| SCHEMBL10192202 | 0.69 | MMP2 (0.53) | MMP2MMP9ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL2968367 | 0.69 | MMP2 (0.41) | MMP2MMP9LMNAKDM4EKEAP1 | |
| SCHEMBL28101490 | 0.68 | RAB9A (0.66) | MMP2MMP9ALDH1A1KDM4EKMT2A | |
| SCHEMBL12994623 | 0.68 | MAPT (0.48) | MMP2MMP9ALDH1A1LMNAKEAP1 | |
| SCHEMBL28516841 | 0.67 | ACHE (0.52) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL3467608 | 0.66 | MAPT (0.63) | ALDH1A1LMNAKDM4EMAPTMCOLN3 | |
| SCHEMBL28895403 | 0.66 | LMNA (0.39) | ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL19651773 | 0.65 | MAPT (0.45) | MMP2MMP9ALDH1A1LMNAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106344552-B | Novel sulfonamide compound, preparation method and application of sulfonamide compound as protein tyrosine phosphatase1B inhibitor | 齐鲁工业大学 | 2021-04-30 | — | — | CN | disclosed |