Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647444 | 0.79 | ESR1 (0.35) | — | |
| SCHEMBL5670628 | 0.76 | LMNA (0.47) | LMNASMN1; SMN2MAPK1HTTALDH1A1 | |
| SCHEMBL8503005 | 0.75 | CA2 (0.43) | KIF11CA1CA2HSD11B1 | |
| SCHEMBL11685641 | 0.72 | LMNA (0.47) | LMNASMN1; SMN2MAPK1HTTALDH1A1 | |
| SCHEMBL10145040 | 0.72 | ALDH1A1 (0.69) | LMNASMN1; SMN2MAPK1HTTALDH1A1 | |
| SCHEMBL10581035 | 0.71 | KCNN4 (0.35) | MAPK1CA1CA2HSD11B1 | |
| SCHEMBL28542275 | 0.70 | LMNA (0.42) | LMNASMN1; SMN2MAPK1HTTALDH1A1 | |
| SCHEMBL8501156 | 0.70 | CA2 (0.42) | HTTALDH1A1KIF11CA1CA2 | |
| SCHEMBL323077 | 0.70 | KIF11 (0.46) | LMNAMAPK1ALDH1A1KIF11POLB | |
| SCHEMBL1719753 | 0.70 | ESR1 (0.54) | LMNAALDH1A1KIF11CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624930-A | Preparation method of 2, 2-bis (4-aminophenyl) hexafluoropropane | 上海如鲲新材料有限公司 | 2021-04-09 | — | — | CN | disclosed |