SCHEMBL2855685

SCHEMBL2855685

COC(=O)[C@@H](N)CCCNC(=O)OC(C)(C)C

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
GAA P10253 1/20 0.62
TDP1 Q9NUW8 2/20 0.53
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
CA1 P00915 9/20 0.48
CA2 P00918 9/20 0.48
CA12 O43570 6/20 0.48
CA9 Q16790 6/20 0.48
STK17B O94768 1/20 0.40
STK17A Q9UEE5 1/20 0.40
ATM Q13315 1/20 0.40
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
EPHX1 P07099 1/20 0.38
DPP7 Q9UHL4 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131062 1.00 MEN1 (0.62) MEN1KMT2AGAATDP1MAOA
SCHEMBL2855689 1.00 MEN1 (0.62) MEN1KMT2AGAATDP1MAOA
Hydrochloric Acid SCHEMBL131061 0.98 MEN1 (0.60) MEN1KMT2AGAATDP1MAOA
Hydrochloric Acid SCHEMBL21271788 0.98 MEN1 (0.60) MEN1KMT2AGAATDP1MAOA
SCHEMBL138402 0.95 MEN1 (0.56) MEN1KMT2AGAATDP1MAOA
SCHEMBL2247530 0.95 MEN1 (0.56) MEN1KMT2AGAATDP1MAOA
SCHEMBL8171267 0.95 MEN1 (0.56) MEN1KMT2AGAATDP1MAOA
Hydrochloric Acid SCHEMBL138401 0.94 MEN1 (0.55) MEN1KMT2AGAATDP1MAOA
Hydrochloric Acid SCHEMBL7352392 0.94 MEN1 (0.55) MEN1KMT2AGAATDP1MAOA
SCHEMBL12215023 0.94 TDP1 (0.58) MEN1KMT2AGAATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528834-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2026-01-20 US disclosed
US-20250312514-A1 COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS ALLERGAN INC (US) 2025-10-09 US disclosed
US-20250114466-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2025-04-10 US disclosed
EP-4457229-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES Byondis B.V. (NL) 2024-11-06 EP disclosed
US-20240316246-A1 COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS ALLERGAN INC (US) 2024-09-26 US disclosed
US-20230277725-A1 COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS ALLERGAN INC (US) 2023-09-07 US disclosed
WO-2023126297-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2023-07-06 WO disclosed
WO-2023126297-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2023-07-06 WO disclosed
US-20230144211-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2023-05-11 US disclosed
US-20230144211-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES BYONDIS B.V. (NL) 2023-05-11 US disclosed
CN-102443048-A Synthetic method of 5-membered cyclopeptide JIANGSU YEW PHARMACEUTICAL CO LTD 2012-05-09 CN disclosed
EP-2119718-B1 MACROCYCLIC COMPOUND CHUGAI PHARMACEUTICAL CO LTD (JP) 2012-04-11 EP disclosed
US-20100120872-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2010-05-13 US disclosed
US-20100120872-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2010-05-13 US disclosed
US-20100056510-A1 Macrocyclic Compound CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2010-03-04 US disclosed
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
EP-2119718-A1 MACROCYCLIC COMPOUND Chugai Seiyaku Kabushiki Kaisha (JP) 2009-11-18 EP disclosed
US-20080188528-A1 Modulators of C3a receptor and methods of use thereof ENCYSIVE PHARMACEUTICALS, INC. 2008-08-07 US disclosed
WO-2008079371-A1 MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF ENCYSIVE PHARMACEUTICALS, INC. (US) 2008-07-03 WO disclosed
EP-1209147-A1 CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT TORAY INDUSTRIES, INC. (JP) 2002-05-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056510-A1 Macrocyclic Compound HSP90AB1, HSP90B1, HSP90AA1 MEN1 2984/4885KMT2A 3546/4885GAA 362/4885
US-20250114466-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES DHFR, FOLR1, MTHFD2 MEN1 1545/4885KMT2A 1224/4885GAA 2610/4885
US-20240316246-A1 COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS CD44, CHIT1, CHIA MEN1 3259/4885KMT2A 4110/4885GAA 357/4885
US-20080188528-A1 Modulators of C3a receptor and methods of use thereof C3AR1, C5, C5AR1 MEN1 2114/4885KMT2A 2978/4885GAA 4404/4885
US-12528834-B2 Method for producing peptide compound VIP, IAPP, NPPA MEN1 355/4885KMT2A 3946/4885GAA 2200/4885
US-20230144211-A1 ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES DHFR, FOLR1, MTHFD2 MEN1 1545/4885KMT2A 1224/4885GAA 2610/4885
US-20100120872-A1 ORGANIC COMPOUNDS AND THEIR USES OAT, OTC, AOX1 MEN1 2302/4885KMT2A 3407/4885GAA 283/4885
US-20250312514-A1 COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS CD44, CHIT1, CHIA MEN1 3259/4885KMT2A 4110/4885GAA 357/4885
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 MEN1 488/4885KMT2A 2996/4885GAA 3279/4885
US-20230277725-A1 COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS CD44, CHIT1, CHIA MEN1 3259/4885KMT2A 4110/4885GAA 357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.