SCHEMBL138402

SCHEMBL138402

COC(=O)[C@@H](N)CCCCNC(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
GAA P10253 1/20 0.56
TDP1 Q9NUW8 4/20 0.55
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
CA1 P00915 9/20 0.50
CA2 P00918 9/20 0.50
CA12 O43570 6/20 0.50
CA9 Q16790 6/20 0.50
ATM Q13315 1/20 0.44
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
DPP7 Q9UHL4 1/20 0.41
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2247530 1.00 MEN1 (0.56) MEN1KMT2AGAATDP1MAOA
SCHEMBL8171267 1.00 MEN1 (0.56) MEN1KMT2AGAATDP1MAOA
Hydrochloric Acid SCHEMBL16486989 0.98 MEN1 (0.55) MEN1KMT2AGAATDP1MAOA
SCHEMBL12215023 0.98 TDP1 (0.58) MEN1KMT2AGAATDP1MAOA
Hydrochloric Acid SCHEMBL7352392 0.98 MEN1 (0.55) MEN1KMT2AGAATDP1MAOA
Hydrochloric Acid SCHEMBL138401 0.98 MEN1 (0.55) MEN1KMT2AGAATDP1MAOA
Hydrochloric Acid SCHEMBL30018358 0.97 TDP1 (0.56) MEN1KMT2AGAATDP1MAOA
SCHEMBL2855685 0.95 MEN1 (0.62) MEN1KMT2AGAATDP1MAOA
SCHEMBL131062 0.95 MEN1 (0.62) MEN1KMT2AGAATDP1MAOA
SCHEMBL2855689 0.95 MEN1 (0.62) MEN1KMT2AGAATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382202-B2 Precursor for labeling therapeutic agent for liver cancer and method for manufacturing the same Atomic Energy Council—Institute of Nuclear Energy Research (TW) 2016-07-05 US claimed
US-20150322005-A1 PRECURSOR FOR LABELING THERAPEUTIC AGENT FOR LIVER CANCER AND METHOD FOR MANUFACTURING THE SAME ATOMIC ENERGY COUNCIL-INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) 2015-11-12 US claimed
EP-3710458-B1 IMMUNOPROTEASOME INHIBITORS PRINCIPIA BIOPHARMA INC (US) 2026-03-25 EP disclosed
US-12551570-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2026-02-17 US disclosed
US-12479927-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2025-11-25 US disclosed
US-20250312514-A1 COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS ALLERGAN INC (US) 2025-10-09 US disclosed
US-20250270162-A1 KETONE INHIBITORS OF LYSINE GINGIPAIN LIGHTHOUSE PHARMACEUTICALS, INC. (US) 2025-08-28 US disclosed
US-20250177582-A1 HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS PHILOCHEM AG (CH) 2025-06-05 US disclosed
CN-120077136-A SiRNA and drug for inhibiting Amyloid Precursor Protein (APP) gene expression and application thereof 广州必贝特医药股份有限公司 2025-05-30 CN disclosed
US-12312370-B2 Immunoproteasome inhibitors PRINCIPIA BIOPHARMA INC. (US) 2025-05-27 US disclosed
US-20250115561-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS PARION SCIENCES, INC. (US) 2025-04-10 US disclosed
US-6211235-B1 ALZHEIMERS DISEASE ELAN PHARMACEUTICALS, INC. 2001-04-03 US disclosed
US-6207710-B1 FOR THERAPY OF ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. 2001-03-27 US disclosed
US-6191166-B1 ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. 2001-02-20 US disclosed
EP-0942924-A2 METHODS AND COMPOUNDS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS Elan Pharmaceuticals, Inc. (US) 1999-09-22 EP disclosed
US-5877030-A REACTING AMINO ACID MOLECULES WITH REACTIVE XANTHENE DERIVATIVES, COMBINATORIAL LIBRARIES SILICON VALLEY BANK 1999-03-02 US disclosed
WO-1998022494-A9 METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS 1998-08-20 WO disclosed
WO-1998022494-A2 METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS ELAN PHARMACEUTICALS, INC. (US) 1998-05-28 WO disclosed
US-4341758-A Immunochemical assay reagent for the determination of haptens, and assay method therewith TEIKOKU HORMONE MFG. CO., LTD. (JP) 1982-07-27 US disclosed
EP-0010405-A1 Stable immunochemical assay reagent for the determination of haptens, and assay method using said reagent TEIKOKU HORMONE MFG. CO., LTD. (JP) 1980-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115561-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS CFTR, SCNN1B, SCNN1G MEN1 4045/4885KMT2A 3783/4885GAA 2003/4885
US-12551570-B2 Compounds comprising cleavable linker and uses thereof FCGR2A, FCGR3B, FCGR1A MEN1 3990/4885KMT2A 3562/4885GAA 1454/4885
US-12312370-B2 Immunoproteasome inhibitors PSMC2, PSMB7, PSMB2 MEN1 3171/4885KMT2A 1002/4885GAA 164/4885
US-20150322005-A1 PRECURSOR FOR LABELING THERAPEUTIC AGENT FOR LIVER CANCER AND METHOD FOR MANUFACTURING THE SAME FABP1, LIPC, HCCS MEN1 542/4885KMT2A 3357/4885GAA 1201/4885
US-20250312514-A1 COACERVATE HYALURONAN HYDROGELS FOR DERMAL FILLER APPLICATIONS CD44, CHIT1, CHIA MEN1 3259/4885KMT2A 4110/4885GAA 357/4885
US-12479927-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 MEN1 3064/4885KMT2A 3544/4885GAA 364/4885
US-20250270162-A1 KETONE INHIBITORS OF LYSINE GINGIPAIN PHYKPL, ENPEP, PREP MEN1 1912/4885KMT2A 300/4885GAA 74/4885
US-20250177582-A1 HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS FAP, FIBP, FGFR1 MEN1 3770/4885KMT2A 4220/4885GAA 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.