Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853175 | 0.92 | KLKB1 (0.43) | P2RX7MAPTKLKB1DGAT2ALDH1A1 | |
| SCHEMBL2852117 | 0.89 | P2RX7 (0.48) | P2RX7MAPTALDH1A1TP53GAA | |
| SCHEMBL2860466 | 0.87 | RCE1 (0.47) | P2RX7MAPTALDH1A1TP53GAA | |
| SCHEMBL2850896 | 0.86 | DGAT2 (0.57) | P2RX7MAPTEPHX2KLKB1DGAT2 | |
| SCHEMBL2856797 | 0.86 | P2RX7 (0.45) | P2RX7ALDH1A1 | |
| SCHEMBL2857544 | 0.85 | TSHR (0.45) | MAPTEPHX2KLKB1DGAT2ALDH1A1 | |
| SCHEMBL2853277 | 0.85 | CCR1 (0.50) | P2RX7KLKB1DGAT2TP53PKM | |
| SCHEMBL2856615 | 0.84 | P2RX7 (0.48) | P2RX7MAPTALDH1A1NPSR1TP53 | |
| SCHEMBL2855708 | 0.84 | P2RX7 (0.44) | P2RX7MAPTDGAT2ALDH1A1NPSR1 | |
| SCHEMBL2859103 | 0.83 | EPHX2 (0.45) | MAPTEPHX2KLKB1DGAT2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |